Evening star. [volume], April 18, 1946, Page B-2, Image 31

About Evening star. [volume] (Washington, D.C.) 1854-1972

Image provided by: Library of Congress, Washington, DC

                
Some Types of Cancer
In Women Traced to
Diet Lacking Thiamine
By Thomas R. Henry
Striking evidence that a deficiency
of vitamins in the diet may be the
primary cause of certain common
forms of cancer in women has just
been presented to the American
Association for the Advancement of
Science here by two Canadian
doctors.
Drs. J. Ernest Ayre and W. A. G.
Bauld of McGill University report
that 18 out of 20 cases of cancer!
of the uterus showed a low level
of thiamine, the most important
element of the ‘vitamin B complex
and a corresponding increase in
one of the growth-stimulating sex
hormones, or estrogens, which is
chemically related to some synthetic
substances known to cause very
deadly malignant growth in ex
perimental animals.
Long Suspected.
These estrogens have cycles of
activity and at other times are in
activated by the liver. The two ex
perimenters present evidence, how
ever, that the liver will not inacti
vate them in cases of deficiency of
the vitamin B complex—chiefly the
substances thiamine and riboflavin.
The female sex hormones long
have been suspected of some role
in cancers of the breast and uterus.
Some of them will cause cancer in
mice. 'This is the first time, how
ever. that the relationship has been
carried a step further back and as
sociated writh the diet.
These types of cancer, the experi
menters point out in their report to
Science, official organ of the asso
ciation, are most frequent in wom
en approaching middle age, when
spartan diets to reduce weight are
in order.
Would Prevent Cycle.
The experiments do not indicate,
they stress, that once a malignant
growth starts additional thiamine in
the diet will be of any value, since
once the vicious cycle is begun it is
able to carry on by itself.
"When we couple the finding with
the background of what has been
proven in animals,” they say, ‘‘there
appears to be excellent circumstan
o
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