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RHEUMATIC CURE NEVER FAILS. VJ- " A3ST ABSOLUTE OTT,E- THE GREAT ALKALINE REMEDY, DR, BOSANKO'S. RHEUMATIC CURE, Universally acknowledged to be the surest, safest, and most permanent cure for that distressing malady ltlicumniiftm ! Thousands of cures attest its merits ! Muscles, Joints, and Tendons brought into normal condition by its use. Immediate relief war ranted ! Permanent cure guaranteed. Now extensively used .by all celebrated physicians of Europo and America, becoming a staple, harmless, and reliable remedy on both continents. The only desolver of tho poisonous Uric Acid which exists in the blood of all rheumatic patients. Where there is an Alkali, there can be no Rheumatism. The Dr. Bo.tuiiko Rheumatic Cure is a chemically prepared Alkaline, neutralizing the acidity and removing chronic inflammation of the Joints by absorption. Rheumatics will experience relief after tho first application, and many cases have been permanently cured by the use of a single bottle. It is a simple external application, which causes no irritation, under whatever ciroumstances applied, thereby producing another pain, but through its penetrating power, it, by absorption, reaches almost at onco the seat of the disease, and gives immediate relief to the sufferer. DR. BOSANKO, a physician of largo practice, and a graduate of one of the most noted medical institutions of Europe, noting that in humid or malarial districts a large proportion of disease was KthcumntiNiii, devoted the greater part of his time and study to the examination and treatment of this " terror of the human frame," and to finding a remedy for this excru ciating malady. His labors resulted in the formulation of his now justly celebrated Jlheiimatlc Cure, which has met with success unpai-alleled in the . history of medi cine during the past ten years, and which has addod now luster to his already brilliant world-wide reputation, and secured to himself the proud distinction, Iing of Chronic Rheumatism. Wo do not claim that tho cure is a panacea for a longf catalogue of diseases, like many others, but know that for Rheumatism alone it is a sovereign remody, and we simply say that it will cure. The success of the cure has been so marfced, its supreme qualities so soon appreciated by sufferers, that wo feel it a paramount duty to push forward a medicine which has already brought the contracted tendons and mus cles, tho stiff and painful joints, and swollen, inflamed- flesh of thousands of rheumatic sufferers into healthy normal action. Cold or damp never produces Rheumatism, but simply develops it, and it is not always dangerous unless it extends to the heart, then the risk is greatly increased. This occurs more frequently when tho disorder has been neglected at the commencement or when unsuitable remedies have been employed. The disease, although not immediately dangerous, will, if not checked, gradually deprive the patient of health, disorganize tho joints, waste tho muscles, and render the patient a cripple perhaps for life. Should you at any time feel a stiffness in tho joints or pain in the bones, particularly of the legs", contraction and soreness of the chords, tendons, and muscles generally, accompanied with more or less redness, swelling, tenderness, and inflammation of the flesh, rest assured that this distressing malady Rheumatism has settled upon you and marked you for a victim. Do not hesitate! For a trifling cost the enemy may be dislodged and defeated before it secures a strong hold upon the system, by the use of Rr. Rosanko Rheumatic Cure. lnJe would also call your attention to osan!t'$ File (Remedy which is a safe, sure, and permanent cure for all kinds of Piles. In general use and not. a failure known. We guarantee this remedy for the most annoying of complaints, often resulting in permanent disability, to be without an equal. It is wonderful to know the amount of suffering that is patiently endured by those afflicted with this disease, who, through false modesty, never make complaint to those who could give them relief. All are liable to be attacked, particularly those whose occupations are sedentary. Piles are frequently preceded by a sense of weight in the back, loins, and lower part of the abdomen, causing the patient to suppose he has some affection of the kidneys or neighboring organs ; at times symptoms of indigestion are present, as flatulency, uneasi ness of the stomach, etc. A moisture like perspiration, producing a very disagreeable itching, particularly at night after getting warm in bed, is a very common attendant. Piles may continue a long time without affecting tho general health, or they may occa sion many disagreeable symptoms, and if not timely attended to, they may produce falling of the bowel, fistula in ano, etc., and instances are not wanting where persons have died from the excessive bleeding accompanying this disease. Fully onerhalf of tho people are, or have been, sufferers from Piles, many without knowing it ; and to all who are predis posed to this disease we confidently assure them that Dr. Rosaulco's Pile Remedy will prevent as well as cure. As soon as a soreness, itching, and signs of inflammation or hard bunches begin to show themselves at the anus, steps to a means of cure should be taken at once, and nothing equals the Rr. Kosanko Remedy. TTJ fQ A "VT7" A'Q Bl?WTTYnrit sPeak for themselves! To try them is to be cured. When you aro unablo to get thoso J1V 33 J 3J.J J.7 XBilTI HTjJjyXJ2il3 goods of your Druggist, and you can not induce him to promptly ordor them for you, by remitting us $3.00 (by draft, money order, or registered letter), we will send you 4 bottles of tho Elieumatic Cure, or 6 of tho Pile Remedy y express, charges paid. Orders for less than this amount will be sent at the expense of the party ordering. To avoid delay give us full directions for shipping. Write plain your name, with your town, county, and State. Ask for Dr. Bosanko's Remedies. Insist upon having them, and take no other. Dr. Bosanko's treatise on Rheumatism and Piles will bo sent to any address, free of charge,' on application. READ THE FOLLOWING TESTIMONIALS AND REFERENCES : Hear what Ex-Mayor Garvcy, an influential and prominent citizen of Piqua says : , ,r ,. . n Piqua, O., Dec. 29, 1879. The Dr. Bosanko Medicine Co. . Gentlemen : I feel under many obligations to you for the relief afforded me by the use of your invaluable medicine, Dr. Bosanko's Rheumatic Cure. I have been for years a sufferer from chronic rheumatism, siifllring at times most excruciating pains, and depriving me of many nights' sleep. After consulting a number of physicians and obtaining no relief, I commenced using your Rheumatic Cure, and after using four bottles, and taking the Blood Purifier in connec tion with it, I am absolutely cured, free from any pain, able to attend to my business, and resting perfectly comfortable at night Respectfully yours, S. B. GARVEY. What tho Cashier ot the First National Bank of Troy, 0., says: i r j- n r- n Troy, O., Dec. 30, 1879. Dr. Bosanko Medicino Co., Piqua, O. ' Gentlemen : I was troubled with Rheumatism last spring in the acute form so badly, that I was unable to use my hand. Through the recommendations of 'my friends, I was induced to try your Rheumatic Cure, which immediately began to soothe, comfort and allay the pain, and in a short time I was relieved of this distressing disease. I take great pleasure in recommending this valuable remedy to those similarly afflicted. Yours, respectfully, JNO. L. MEREDITH. Suffered from Rheumatism for fifteen years: J. C. Wadleich, with E. H. Sargent & Co., Wholesale Druggists, 125 State Street Chicago, says: I am sixty years old and have suffered from Rheumatism for fifteen years. By the use of two bottlea of your valuable cure, I am better than I have been in the last ten years, and continue to improve. I feel as though I would once more be free from that most painful of all diseases, rheumatism. 4 It cured her when other medicines had failed : Piqua, O., April 30, 1879. The Dr. Bosanko Medicine Co. Gentlemen : 1 wish to thank you for the great benefit my wife derived from your Pile Remedy. It cured her when other medicines had failed. I have no hesitancy in recommending this incomparable medicine to my friends. Most gratefully yours, ' THOMAS W. DEWEESE. Cured after the use of a single bottle: TilOY, O., March 10, 1879. The Dr. Bosanko Medicine Co., Piqua, O. Gentlemen : I have been afflicted with rheumatism for more than four years. I have employed phyaicians, and used several kinds of patent medicines with no permanent relief. Finally I was induced to make a trial of your " Rheumatic Cure," and I am happy to say that I can pronounce myself cured after using but one bottle. Relief experienced after the first two or three applications. Yours truly, ELLIOT MILLER, Bookseller and Stationer. National Military Home for disabled Volunteer Soldiers: Dayton, O., Sept. 11, 1879. The Dr. Bosanko Medicine Co., Piqua, O. The undersigned certify, that after the use of two bottles of Dr. Bosanko's Rheumatic Cure, the pain and inflammation of the parts affected was removed, and that they were able to walk quite a distance. Having been deprived of the use of their limbs before using said medicine, they cheerfully recommend the Dr. Bosanko's Rheumatic Cure as the best medicine iu use for that terrible disease. GEO. F. KUHLES, A rheumatic sufferer for sixteen years. JOSEPH SIIULTZ, A rheumatic sufferer for eighteen years. What the druggists say of these remedies : Owosso, Mich., Sept. 20, 1879. Dr. Bosanko. Dear Sir: Please send us two dozen of your Rheumatic Cure. It is taking well here, and appears to be doing wonders. Send as soon as possible and oblige, Respectfully yours, OSBORN BROS. By Telegraph: Owosso, Mich., Oct. 7, 1879. Dr. Bosanko Medicine Co., Piqua, O. Express us two dozen of your Rheumatic Cure on first train. OSBORN BROS. Paul Oracf, Jr., Druggist, Piqua, 0., says: I invariably recommend your medicines to my customers, for the reason that they perform all that is claimed for them. Says it is the best in use : Ho bart, Mick ov. 13, 1879. Dr. Bosanko Medicine Co., Piqua, O. Gentlemen : Enclosed find check on Grand Rapids for $40.50, the amount of my bill. Send me two dozen of your Rheumatic Cure. It is the best in use. Respectfully yours, W.-H. CUSHIN3. Cottingham Si Sterrett, Druggists, Troy, O., says : They never , fail in rendering entire satisfaction to all who have tried them. C. T. Armstrong, Druggist and physician, Corunna, Mich., says: Your Pile Remedy has given first class satisfaction. For want of space we append the names of only a few of the numerous patrons at home and abroad, who have tried and testified to the merits of our remedies, and respectfully refer to them. C. Langdon, Cashier Pinua National Bank. M. Friedlich, Vice-President Citizens National Bank, Piqua, O. V. M. Pursell, of John O'Ferrall & Co., Piqua Car aud Agricul tural Implement "Works. H. K. "Wood, of Wood, Farrington & Co., Linseed Oil Manufact urers, Piqua, O. B. Upton, of Upton & George, Coal Merchants, Piqua, O. E. D. Baxter, Agent P. C. & St. L. R. R., Piqua, O. B. F. Brown, Ex-County Commissioner, Piqua, (). Win. Patterson, Piqua, O. J. Z. Stephens, of lleywood, Gearhart & Stephens, Agricultural Implement Agenoy, Troy, O. J. T. Tlwmpson, Undertaker, Troy, O. David Miller, Gunsmith, Troy, O. A. D. McPherson, Troy, O. J. W. Hottel, Troy, O. John E. Henne, Troy, O. John Upton, Telegraph Operator, Urbana, O. John Ranch, Urbana, O. I. J. Friodlander, of Ileidelbach, Friedlander & Co., Cincinnati, O. Sol. Goldsmith, of Mack, Stadler & Co., Cincinnati, O. Martin Guiterman, with A. & J. Trounstine & Co., Cinoinnati, O. Lewis Stern, of Lewis Stern & Co., Chicago, Ills. Manufactured by the DR. BOSANKO MEDICINE CO., Piqua, Ohio, U. S. A., to whom all orders should be addressed. These Remedies are for Sale by TAYLOR & MILLER, Druggists, Perrysburg, Ohio,